Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persis… (NCT06091280) | Clinical Trial Compass
CompletedNot Applicable
Home-Based Respiratory Muscle Strength Training Program for Individuals With Post-COVID-19 Persistent Dyspnea
United States25 participantsStarted 2023-12-01
Plain-language summary
To evaluate the extent to which a 12-week respiratory rehabilitation program consisting of inspiratory and expiratory breathing exercises compared to expiratory breathing exercises alone will help to improve shortness of breath, respiratory symptoms, breathing function, distance walked, and quality of life in those who are experiencing persistent shortness of breath after having had COVID-19. Measurements will take place at the beginning, 6 weeks, and at 12 weeks in the study.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Self-reported history of a positive COVID-19 diagnosis in the past.
* Able to walk independently
* Cognitively intact
* English-speaking
* Dyspnea at rest or with activity rated at 3 or greater on the Dyspnea on Exertion scale.
* May use oxygen.
* May be taking medications.
Exclusion Criteria:
* Individuals who are wheelchair bound or who cannot walk independently.
* Individuals hospitalized for COVID-19 who self-report that they received mechanical ventilation during hospitalization.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Modified Medical Research Council Scale
Timeframe: Baseline, 6-weeks, and 12-week measurements
2
COPD Assessment Test
Timeframe: Baseline, 6-weeks, and 12-week measurements.
3
Forced Expiratory Volume over 1 second (FEV1)
Timeframe: Baseline, 6-weeks, and 12-week measurements
4
Peak Inspiratory Flow
Timeframe: Baseline, 6-weeks, and 12-week measurements.
5
Thoracic Expansion Measures
Timeframe: Baseline, 6-weeks, and 12-week measurements
6
Physical Capacity
Timeframe: Baseline, 6-weeks, and 12-week measurements.
7
EuroQoL-5 Dimension-5 Level
Timeframe: Baseline, 6-weeks, and 12-week measurements.