CompletedNot Applicable

Pain Relieving Potentials of Combination of Oral Duloxetine and Intravenous Magnesium Sulphate in Post Mastectomy Pain

Egypt90 participantsStarted 2023-10-10

Plain-language summary

This study aims to evaluate the effect of combined duloxetine and IV Magnesium sulphate to decrease acute and chronic post mastectomy pain. The study will be conducted in National Cancer Institute and all the participants will be enrolled from female patients scheduled for modified radical mastectomy under general anesthesia in National Cancer Institute, Cairo University.

Who can participate

Age range18 Years – 65 Years

SexFEMALE

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Inclusion Criteria: * Age from 18 to 65 years old. * American Society of Anesthesiologists (ASA) physical I-II * Scheduled for modified radical mastectomy (MRM) under general anesthesia. Exclusion Criteria: * Liver or kidney disease * Patient with previous chronic pain on opioids * Patients on antidepressants and antipsychotics. * Allergies to study drugs

What they're measuring

Time to first analgesic request

Timeframe: 48 hours postoperatively

Trial details

NCT IDNCT06087211

SponsorNational Cancer Institute, Egypt

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2025-01-01

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