Intestinal & Multivisceral Transplantation for Unresectable Mucinous Carcinoma Peritonei (TRANSCAPE)

Inclusion Criteria: * Subjects must have histologically confirmed pseudomyxoma peritonei (PMP) * Both low-grade mucinous carcinoma peritonei (LMCP) or high-grade mucinous carcinoma (HMCP), with or without signet ring cells as well as primary or recurrent disease, will be eligible. * PMP disease does not have any extra-abdominal metastases, with the exception of pulmonary involvement (nodal, parenchymal, and pleural). * PMP disease is extensive and not amenable to operative management, with or without liver, pancreas, stomach, or abdominal wall involvement. * Definition of Non-Resectable Disease- * Non-resectable PMP disease will be defined as the presence of at least one of the following conditions: * 1\) Extensive small bowel serosa involvement, where it is not possible to preserve at least 1.5-2 m of small bowel * 2\) Extensive infiltration of the pancreatic surface * 3\) Mesenteric involvement causing retraction * 4\) Need for complete gastric resection * 5\) Urete1ic obstruction * 6\) Liver disease with no chance to achieve R0 resection with liver remnant volume \> 30% * 7\) Recurrent disease not amenable to further resection * Subjects do not have any other available curative treatment options. * Subjects can have previous abdominal operations, including CRS+HIPEC. * Age ≥ 18 and ≤ 75. * Pediatric participants were excluded as PMP is a disease that affects adults. Participants \> 75 years of age are excluded as…