Correlation Between Perioperative EEG Features and Delirium After General Anesthesia (NCT06082024) | Clinical Trial Compass
UnknownNot Applicable
Correlation Between Perioperative EEG Features and Delirium After General Anesthesia
China40 participantsStarted 2023-04-13
Plain-language summary
The goal of this observational study is to compare the perioperative EEG characteristics and the incidence of short-term cognitive dysfunction in patients with postoperative delirium and non-postoperative delirium after elderly (\> 65 years old) patients undergoing major gastrointestinal surgery under general anesthesia. The main question it aims to answer are: • The correlation between postoperative cognitive dysfunction and postoperative EEG features was evaluated.• To analyze the correlation between EEG characteristics and clinical risk factors of delirium after major abdominal gastrointestinal surgery under general anesthesia in elderly patients.Participants will collect EEG before and after operation and collect the incidence of postoperative cognitive function to explore the mechanism of postoperative delirium and predict postoperative cognitive dysfunction.
Who can participate
Age range
65 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion criteria
. Education level in primary school or above;
. Age ≥65 years old, gender is not limited;
. Good communication ability, language expression ability, mental state and consciousness state;
. Preoperative simple mental state scale score ≥27 points;
. no history of craniocerebral diseases;
. For patients who plan to choose abdominal surgery under general anesthesia, the operation time is expected to be about 2h-4h;
. ASA anesthesia grade I \~ III;
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
wave time-frequency analysis
Timeframe: one day before surgery, 7-10 days after surgery
2
P300 latency and peak changes
Timeframe: one day before surgery, 7-10 days after surgery
3
EEG event-related potential accuracy and response time
Timeframe: one day before surgery, 7-10 days after surgery
4
Incidence of postoperative short-term cognitive dysfunction
. Relative contraindications of general anesthesia: patients with serious heart and lung function diseases, drug allergy history, etc.
. Patients with a history of mental illness or long-term psychiatric drugs (dementia, schizophrenia), chronic analgesic drug use history, alcoholism history and cognitive dysfunction;
. any cerebrovascular accident occurred within 3 months, such as stroke, transient ischemic attack (TIA), etc.
. Diabetic patients with severe diabetic complications (diabetic ketoacidosis, hyperosmolar coma, various infections, macrovascular disease, diabetic nephropathy);
. Chronic hypoxia and carbon dioxide storage, such as chronic obstructive emphysema;
. a long history of alcohol abuse;
. Unable to cooperate to complete the test, the patient or family rejected the participant.