Perineural Dexamethasone in the Adductor Canal Block (NCT06079047) | Clinical Trial Compass
CompletedNot Applicable
Perineural Dexamethasone in the Adductor Canal Block
Tunisia66 participantsStarted 2023-12-15
Plain-language summary
Postoperative pain management in total knee arthroplasty (TKA) surgery is a real challenge for the anesthesiologist. Effective pain control must be provided while preserving the mobility to ensure early rehabilitation. The adductor canal block is an effective way to induce sensory block without motor block. However, the major disadvantage of this block is the duration of sensory block which may be insufficient for postoperative pain management in TKA surgery. Many studies have focused on finding molecules that can prolong sensory block without the need for a perineural catheter and dexamethasone is among the most studied molecules(1, 2). Hence, our study aims to evaluate the added value of perineural dexamethasone in the adductor canal block in TKA surgery.
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Who can participate
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients scheduled for unilateral TKA
* Surgery under spinal anesthesia
* ASA class I, II, and III patients
Exclusion Criteria:
* Patient refusal to participate in the study
* Contraindication to regional anesthesia
* Allergies to the products used
* Bilateral TKA
* Revision TKA
* TKA in the context of inflammatory or post-traumatic disease
* BMI \> 45
* Poorly controlled diabetic patients with HbA1c \> 8%
* Patients on corticosteroid therapy or who have received an intra-articular injection of corticosteroids
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial tested adding dexamethasone directly to a nerve block called the adductor canal block — is that type of nerve block something that would be used during my surgery, and if so, could adding dexamethasone to it actually reduce how much morphine I'd need afterward?
2Since this study has already been completed, has my care team seen or reviewed any of its findings on morphine consumption, and do the results suggest this approach works better than a standard adductor canal block without dexamethasone?
3The trial focused on post-operative pain control specifically — how does using a nerve block with dexamethasone compare to the pain management plan you're already considering for me, and would it offer any real advantage?
4Given that dexamethasone is being injected directly around a nerve rather than given by mouth or IV, are there any specific risks with that approach I should know about before deciding whether to ask about it for my own procedure?
5If this technique reduces opioid use after surgery, could that also mean fewer opioid side effects like nausea or drowsiness during my recovery, and is that something worth factoring into my pain management plan?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.