Neglect Treatment by Prism Adaptation in the Acute Phase (NCT06078111) | Clinical Trial Compass
RecruitingNot Applicable
Neglect Treatment by Prism Adaptation in the Acute Phase
Switzerland32 participantsStarted 2023-11-01
Plain-language summary
This project aims at unveiling the beneficial effects of prism adaptation as early rehabilitation technique to treat unilateral spatial neglect in the acute phase after a brain damage. This syndrome, frequent and very invalidating for daily life activities after a brain damage, is a cognitive disorder of lack of attention towards a part of the space. Patients at a first event brain injury hospitalized into the Neurology and Neurosurgery Departments and affected by spatial neglect will undergo to a protocol of five consecutive rehabilitation treatments, being assigned to the experimental (prisms) or control groups (neutral prisms). The effectiveness of the treatment will be assessed with cognitive, functional and motor-related measures, as well as a follow up 3 months later. These results can have a strong impact on the long-term functional outcome of these patients.
Who can participate
Age range
18 Years – 90 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* First neurological event, affecting the right hemisphere or the left hemisphere (stroke, brain tumour post-surgery);
* Structural images of the brain lesion available (magnetic resonance or tomographic scans);
* Good Normal (or corrected) visual acuity;
* Presence of USN, as assessed by a standard neuropsychological evaluation.
Exclusion Criteria:
* Previous neurological disorder and/or current or previous psychiatric disease.
* Presence or suspicion of previous general cognitive deficits documented from the clinical dossier and/or suspicious of possible cognitive deficits ;
* Presence of difficulty in task's comprehension preventing its completion;
* Impossibility to sustain a research session of at least 30 minutes (e.g., attentional lability).
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Unilateral spatial neglect
Timeframe: Day 0; Day 5; 12 weeks after the end of the protocol
2
Functional measures
Timeframe: Day 0; Day 5; 12 weeks after the end of the protocol
3
Disability measures
Timeframe: Day 0; Day 5; 12 weeks after the end of the protocol
4
Balance
Timeframe: Day 0; Day 5; 12 weeks after the end of the protocol