Leveraging Psychological Autopsies to Accelerate Research Into Stimulant Overdose Mortality (NCT06076564) | Clinical Trial Compass
CompletedNot Applicable
Leveraging Psychological Autopsies to Accelerate Research Into Stimulant Overdose Mortality
United States176 participantsStarted 2022-06-06
Plain-language summary
In the LASSO study, the investigators will identify 100 stimulant overdose decedents (divided among stimulant-only, and stimulant with fentanyl), conduct informant interviews (including scales and qualitative data), and gather data from the postmortem investigation (e.g., vital records, toxicology, autopsy, case narrative, death scene photographs) and medical record abstraction. Subsequently, study staff will conduct qualitative interviews with 40-60 living people who use stimulants (aiming for half methamphetamine, half cocaine) to explore elements of resilience and risk reduction strategies. This study aims to contribute to the eventual design of interventions to reduce stimulant overdose mortality.
Who can participate
Age range18 Years
SexALL
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Inclusion criteria
ā. are aware the decedent used substances in the past year prior the to date of death AND
ā. have been in contact with the decedent in the past year prior to the date of death by phone, email, or in person
ā. are aware the decedent used substances in the past 30 days prior to the date of death and
ā. have been in contact with the decedent in person in the past year prior to the date of death.
ā. ā„18 years of age,
ā. Used cocaine or methamphetamine for ā„5 years,
ā. Used cocaine or methamphetamine for ā„10 out of the past 30 days, AND
ā. Matched to a decedent on age, race/ethnicity, gender, and neighborhood distribution of decedents of the methamphetamine/no opioid and cocaine/no opioid decedents.
Exclusion criteria
ā. Used both cocaine and methamphetamine ā„5 of past 30 days,
What they're measuring
1
Clinical antecedents to stimulant overdose.
Timeframe: One year prior to the date of death.
2
Antecedent patterns between stimulant overdose deaths with and without fentanyl.
Timeframe: One year prior to the date of death.
3
Resilience factors and risk reduction strategies among living persons who use stimulants.