RecruitingPhase 1

Greater Occipital Nerve Blockade in Veterans With Post-concussion Headache: Sub-study 1

United States12 participantsStarted 2024-01-26

Plain-language summary

The acute and subacute sensations that occur on the scalp with injection of different concentrations of bupivacaine for grater occipital nerve blockade will be compared. Each Veteran participant will be randomized to receive three different concentrations, which will be injected one week apart each.

Who can participate

Age range18 Years

SexALL

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Exclusion criteria

✕. Allergy or adverse reaction (e.g., rash, cardiac effects) to amide anesthetics, such as lidocaine
✕. Instruction from clinician to avoid amide anesthetics, such as lidocaine

What they're measuring

Acute sensation felt during injection: quality

Timeframe: During injection

Acute sensation felt during injection: intensity

Timeframe: During injection

Paresthesia felt after injection: quality

Timeframe: From the time of injection to 1 week after injection

Paresthesia felt after injection: intensity

Timeframe: From the time of injection to 1 week after injection

Paresthesia felt after injection: distribution

Timeframe: From the time of injection to 1 week after injection

Paresthesia felt after injection: duration

Timeframe: From the time of injection to 1 week after injection

Trial details

NCT IDNCT06069791

SponsorYale University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-12-31

Contact for this trial

Emmanuelle Schindler, MD, PhD

203-932-5711 emmanuelle.schindler@va.gov

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