Not Yet RecruitingNot Applicable

Closed Incision Negative Pressure Wound Therapy for the Prevention of Surgical Site Infections in Abdominal Surgery

Switzerland654 participantsStarted 2026-03-01

Plain-language summary

Surgical site infections (SSI) are a frequent complication in abdominal surgery. SSI lead to worse outcomes for the affected patients and significantly higher healthcare costs. Closed incision negative pressure wound therapy (ciNPWT) consists of a non-invasive, vacuum-assisted system that applies negative pressure to closed surgical incisions. It is currently unclear, if ciNPWT reduces SSI in patients undergoing abdominal surgery. This trial will investigate the effect of ciNPWT on SSI in abdominal surgery.

Who can participate

Age range19 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Elective or emergency laparotomy, or laparoscopy converted to laparotomy, including surgery for complications after elective operations * Incision length ≥ 10 cm * Centers for Disease Control and Prevention (CDC) wound class 1 and 2 (clean, clean-contaminated) * Abdominal closure with or without mesh implantation * Primary abdominal closure or closure after open abdomen treatment * Age over 18 years * Written informed consent Exclusion Criteria: * Age ≤ 18 years * CDC wound class 4 (dirty/infected wound) * Organ transplantation * Sensitivity or allergy to silver

What they're measuring

Composite incidence of superficial and deep surgical site infections

Timeframe: 30 (+/- 7) days

Trial details

NCT IDNCT06068517

SponsorInsel Gruppe AG, University Hospital Bern

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-10-31

Contact for this trial

Tobias Haltmeier, MD

31 664 03 04 tobias.haltmeier@insel.ch

View on ClinicalTrials.gov More Surgical Wound Infection trials