An mHealth Intervention to Improve HIV Prevention Service Engagement Among People Who Use Drugs (NCT06068283) | Clinical Trial Compass
Not Yet RecruitingNot Applicable
An mHealth Intervention to Improve HIV Prevention Service Engagement Among People Who Use Drugs
United States40 participantsStarted 2026-07-01
Plain-language summary
The goal of this single arm pre-post study is to assess the feasibility, acceptability, and preliminary impact of the LOTUS intervention to improve HIV prevention service engagement among people who use drugs. LOTUS is a technology-delivered intervention that provides HIV prevention informational content and tips, peer social support and social networking features, a resource locator, HIV prevention monitoring and reminders (e.g., reminders for HIV/STI testing and PrEP doses), and a virtual space to have questions answered by health care professionals.
Who can participate
Age range
18 Years
Sex
FEMALE
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 18 years of age or older
* Report weekly or daily use of opioids and/or stimulants in the past 6 months
* Meet current CDC eligibility criteria for PrEP
* Report low levels of HIV prevention service engagement in the past 6 months
* Not currently, or planning on becoming, pregnant during the study
* Owns a smartphone with internet web-browsing capabilities
Exclusion Criteria:
* 17 years of age or younger
* Does not report weekly or daily use of opioids and/or stimulants in the past 6 months
* Does not meet current CDC eligibility criteria for PrEP
* Report high levels of HIV prevention service engagement in the past 6 months
* Currently, or planning on becoming, pregnant during the study
* Does not own a smartphone with internet web-browsing capabilities
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.