CompletedNot Applicable

Effects of Chlorhexidine Toothpaste on Wound Healing After Impacted Tooth Extraction

Turkey (Türkiye)22 participantsStarted 2020-03-04

Plain-language summary

In this study, the postoperative clinical and microbiologic effects of chlorhexidine toothpaste and chlorhexidine-free toothpaste with the same content were compared after bilateral mandibular impacted third molar surgery. Similarly positioned fully impacted impacted lower third molars were extracted. Bilateral impacted wisdom teeth of the patients were randomly selected. After the operation, the experimental group received Dentasave 0.2% chlorhexidine toothpaste containing chlorhexidine and the control group received toothpaste with the same content but without chlorhexidine. Teeth were extracted by the same dentist at 14-day intervals. For microbiological analysis, saliva samples were taken before the first tooth extraction, before the second tooth extraction 14 days later and on the 28th day and sent to the microbiology laboratory. Wound healing, edema and trismus in both extractions were evaluated 1 week after tooth extraction. Wound healing was evaluated as good, acceptable and poor. VAS (Visual Analog Scale) was used for pain assessment and recorded 14 days after tooth extraction.

Who can participate

Age range

18 Years – 31 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Volunteers with bilateral fully impacted mandibular wisdom teeth Exclusion Criteria: * Patients were excluded from the study if they did not understand the clinical procedures of the study, * Had allergies or intolerance to any of the substances used in the study, * Patients on anticoagulant or psychiatric treatment, * Pregnant or breastfeeding, * Patients using oral contraceptiveswere, * Diabetic, * Patients with periodontal disease or active infection * Smokers of more than 10 cigarettes per day, * Poor oral hygiene

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Mouth opening measurements

Timeframe: 0-28 days

Facial edema

Timeframe: 0-28 days

Wound healing

Timeframe: 0-28 days

Visual Analog Scale

Timeframe: 0-28 days

Microbiological analysis

Timeframe: 0-28 days

Trial details

NCT IDNCT06067542

SponsorYuzuncu Yil University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2021-03-20

View on ClinicalTrials.gov More Tooth Impaction trials

Plain-language summary

Who can participate

Age range

18 Years – 31 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.