Renal Cell Arrest and Damage Biomarkers in Progression and Outcome of Septic AKI

Inclusion Criteria: * AKI stage 1 or 2 according to KDIGO definition. * Sepsis is defined based on the third international consensus definitions for sepsis and septic shock (Sepsis-3) as life threatening organ dysfunction caused by a dysregulated host response to infection. At least two of systemic inflammatory response syndrome (SIRS) criteria should be present Exclusion Criteria: * Age less than 18 years. * Patients with pre-existing chronic kidney disease (eGFR\<60 ml/min/1.73m2). * Previous renal replacement therapy. * Acute kidney injury caused by permanent postrenal obstruction. * Pregnancy. * Hepatorenal syndrome. * Renal transplant recipients. * Patients for whom survival to 30 days is unlikely due to end stage disease (end stage liver or heart disease or untreatable malignancy).