Effect of Gum Chewing on Sore Throat After Double-lumen Tube Intubation (NCT06061250) | Clinical Trial Compass
WithdrawnNot Applicable
Effect of Gum Chewing on Sore Throat After Double-lumen Tube Intubation
Stopped: The study has not commenced due to medical staff strikes and staffing shortages.
0Started 2023-10-24
Plain-language summary
Patients undergoing video-assisted thoracoscopic surgery requiring double-lumen tube intubation are randomized into two groups; gum group and control group. In the gum group, patients are instructed to chew gum for 2 minutes, approximately 10 minutes before induction of anesthesia. Patients in the control group are instructed to swallow saliva twice. Postoperative sore throat and hoarseness are assessed 30 minutes after recovery room admission, and at 2 and 24 hours after extubation.
Who can participate
Age range
19 Years – 75 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Patients aged 19-75 years undergoing routine video-assisted thoracoscopic surgery scheduled for double-lumen tube intubation
* Patients who are able to provide written informed consent to participate in the study and understand the procedures of this study
* American Society of Anesthesiologists physical status classification (ASA physical status classification) grade 1-2
Exclusion Criteria:
* Patients who have not consented to the study
* American Society of Anesthesiologists physical status classification (ASA physical status classification) grade 3-4
* Patients with poor dental health that limits chewing gum or tracheal intubation
* Patients who are expected to be difficult to intubate
* Patients with a history of aspiration pneumonia
* Patients being treated for chronic laryngitis, chronic bronchitis, asthma, reflux esophagitis
* Patients with a history of smoking within the past week
* Patients who have difficulty communicating or carrying out gum chewing and spitting instructions
* Patients with hypersensitivity to Xylitol gum ingredients
* Patients taking narcotic analgesics, antidepressants, and anticonvulsants for chronic pain
* Patients requiring endotracheal intubation or intensive care unit treatment after surgery
* Patients who, in the opinion of the investigator or study staff, are not appropriate candidates for this study
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Incidence of postoperative sore throat at 24 hours after extubation