CompletedNot Applicable

Effects of Multimodal Physical Therapy in Patients With Lumbosacral Radiculopathy

Egypt14 participantsStarted 2018-06-01

Plain-language summary

Purposes of the study To investigate the effect of Multimodal Physical Therapy on pain, daiablility H-reflex, and Diffusion Tensor Imaging (DTI) Parameters in Patients With Lumbosacral Radiculopathy.

Who can participate

Age range

20 Years – 45 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * chronic (≥ 3 months) unilateral Lumbosacral Radiculopathy (LSR) * The LSR is due to paracentral L4-L5 or L5-S1 Lumbar disc herniation * The LSR is confirmed radiologically by MRI * The LSR is confirmed clinically by history and physical examination * The LSR is confirmed neurophysiological by soleus H-reflex assessment * Body mass Index less than 30 * 20-45 years of age Exclusion Criteria: * systematic disease * Bilateral symptoms * Lumbar spinal stenosis * previous surgery * Steroid injection * Spinal fracture * Lumbar spinal stenosis * Spinal deformity * Spinal fracture * Radiological evidence of bilateral nerve root encroachmen * Evidence of H-reflex amplitude or latency affection on asymptomatic side

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Pain

Timeframe: Change from Baseline pain at 6 weaks

Disability

Timeframe: Change from Baseline Disability at 6 weaks

Soleus H-reflex amplitude

Timeframe: Change from Baseline Soleus H-reflex amplitude at 6 weaks

Soleus H-reflex side-to-side amplitude (H/H) ratio

Timeframe: Change from Baseline Soleus H/H ratio at 6 weaks

Fractional anisotropy (FA) of the compressed nerve root

Timeframe: Change from Baseline Fractional anisotropy (FA) ratio at 6 weaks

Apparent diffusion coefficient (ADC) of the compressed nerve root

Timeframe: Change from Baseline Apparent diffusion coefficient (ADC) at 6 weaks

Trial details

NCT IDNCT06058806

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2020-01-20

View on ClinicalTrials.gov More Lumbosacral Radiculopathy trials