UnknownNot Applicable

Frequency ,Etiology and Prognostic Factors of Acute Transverse Myelitis

50 participantsStarted 2023-12

Plain-language summary

To identify the frequency of ATM and its different aetiologies, alongside the different clinical and radiological patterns and prognostic factors .

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

✓. Sensory, motor, or autonomic dysfunction originating from the spinal cord
✓. T2 hyperintense signal changes on MRI
✓. No evidence of a compressive lesion
✓. Bilateral signs/symptoms.
✓. Clearly defined sensory level.
✓. Evidence of inflammatory process demonstrated by gadolinium enhancement on MRI, cerebrospinal fluid (CSF) analysis showing pleocytosis, or elevated immunoglobulin G (IgG) index.
✓. Progression to nadir between 4 hours and 21 days.

✕. An alternative diagnosis became apparent any time along the study period including evidence of compressive lesion in MRI, history of previous radiation to the spine within the past 10 years, clinical deficit consistent with thrombosis of the anterior spinal artery or Abnormal flow voids on the surface of the spinal cord consistent with AVFs.
✕. Incomplete clinical, laboratory or radiographic data.
✕. Patients refused to sign the informed consent

Determine the relative frequency of different aetiologies of ATM among Southern Egyptian patients attending Assiut University Hospital

Timeframe: 1 year

NCT IDNCT06055998

SponsorAssiut University

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2024-12

Fouad E Fawaz, Resident