CompletedNot Applicable

To Study the Effects of Mango Ingestion in T2DM and Non-diabetic Subjects.

India130 participantsStarted 2022-02-11

Plain-language summary

T2DM patient will be recruited from endocrine OPD 1. Clinical History and Examination: 1. General Physical Examination: * Height (cm) * weight (kg) * BMI (kg/m2) * Blood Pressure (mmHg) 2. Anthropometry: Circumferences and skinfold thickness will be recorded for the patients in the following manner. Circumferences: * Waist circumference (cm) * Hip circumference (cm) * Mid-arm circumference (cm) * Mid-thigh circumference (cm) 3. Skin fold thickness: Skin fold thickness will be measured by using (LANGE skin fold calipers) (to nearest of 1 mm) at the following sites * Biceps (mm) * Triceps (mm) * Thigh (mm) * Calf (mm) * Sub scapular (mm) * Supra-iliac (mm) * Anterior axillary fold. (mm) 2. Biochemical Test: The biochemical analysis will be done using ELISA kit or commercially available kits * Blood glucose (mg/dL) * HbA1c (%) * Serum insulin (μIU/mL) * Total Cholestrol (mg/dl) * Triglyceride (mg/dl) * Fructosamine (umol/L) * Adiponectin (µg/ml) -- HOMA-IR 3. Body Composition Analysis (TANITA)

Who can participate

Age range

25 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

For patients with diabetes: Stable glycemic control on metformin or sulfonylurea for past 3 months and without any major complications and HbA1C less than 8%

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Outcome for all the phases will be as follows

Timeframe: Baseline, after six months of intervention

Postprandial blood glucose (mg/dL)

Timeframe: Baseline, after six months of intervention

Glycemic indices as per Continuous glucose monitoring system (CGMS) & HbA1c (%)

Timeframe: Baseline, after six months of intervention

Trial details

NCT IDNCT06055582

SponsorDiabetes Foundation, India

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2023-02-15

View on ClinicalTrials.gov More Normoglycemia trials

Plain-language summary

Who can participate

Age range

25 Years – 60 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion criteria

For patients with diabetes: Stable glycemic control on metformin or sulfonylurea for past 3 months and without any major complications and HbA1C less than 8%

What they're measuring

Outcome for all the phases will be as follows

Timeframe: Baseline, after six months of intervention

Postprandial blood glucose (mg/dL)

Timeframe: Baseline, after six months of intervention

Glycemic indices as per Continuous glucose monitoring system (CGMS) & HbA1c (%)

Timeframe: Baseline, after six months of intervention