Platelet Rich Plasma on Ovarian Reserve Parameters and Intra Cytoplasmic Sperm Injection Outcomes in Patients With Diminished Ovarian Reserve

Inclusion Criteria: * Women under the age of 40. * have been infertile for more than a year * have had at least one previous unsuccessful (or cancelled) IVF cycle. * having one of the criteria of poor ovarian response including anti mullerian hormone (AMH) level \<1.1 ng /ml ,the antral follicle count of two ovaries in vaginal ultrasound \<7 . Exclusion Criteria: * pregnancy(ruled out and documented before PRP injection) . Hydrosalpinex,uterine malformations and abnormal uterine cavity. * Partner with severe male factor * Ongoing malignancy. * Chronic pelvic pain * A history of major lower abdomen surgeries that resulted in pelvic adhesions.