Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair (NCT06042933) | Clinical Trial Compass
CompletedNot Applicable
Early Oral Feeding Versus Traditional Delayed Oral Feeding Post-perforated Peptic Ulcer Repair
Egypt100 participantsStarted 2023-03-02
Plain-language summary
This study aims to evaluate safety and benefits of early oral feeding compared to traditional delayed oral feeding in patients undergoing perforated peptic ulcer repairs. Study population \& Sample size :(
Who can participate
Age range18 Years
SexALL
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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
\- All consecutive patients, of age 18 years and above, who were
presented to the emergency surgical team and were diagnosed with perforated duodenal ulcer by surgicalteam, were recruited and assessed for eligibility.
Exclusion Criteria:
* • Preoperative refractory septic shock on admission.
* Delayed presentation more than 24 hours.
* The presence of neuropsychiatric disease, pregnant and lactating women.
* Predisposing factors for impaired wound healing (e.g., currently using immunosuppressive agents, or chronic use of steroids), the presence of HIV.
* American society of anesthesiologists grade iii/iv, or had an alternative perioperative diagnosis.
* Intraoperatively, after randomization, patients were excluded based on the following criteria: perforated duodenal ulcer ≥20 mm, consistent with malignant ulcers.