UnknownNot Applicable

Application of Brachial Plexus Block in Patients Undergoing Cerebral Aneurysm Embolization Via Transradial Approach

China176 participantsStarted 2023-06-01

Plain-language summary

The aim of this study was toinvestigate the effect of BPB on outcome of upper extremity arteries in patients undergoing interventional embolization of intracranial aneurysms via TRA. A multicenter prospective clinical trial was designed. The study subjects were patients undergoing cerebral aneurysm embolization with TRA. BPB was given in the BPB group patients and no BPB in the control group.The incidence of radial artery spasm (RAS) diagnosed by intraoperative angiography and the occurrence of the unfavorable RA for repeated trans-radial interventions (TRI) diagnosed by vascular ultrasound 1 month after surgery， perioperative changes of blood flow parameters in upper limb vessels,postoperative inflammatory factors and complications were observed in the two groups.

Who can participate

Age range

18 Years – 75 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * 18-75 years old, BMI\<28kg/m2 * ASA physical status Ⅰ-Ⅲ * Elective interventional surgery for intracranial aneurysms via TRA * willing to sign informed consent Exclusion Criteria: * patients allergic to local anesthetics * neck infection on the surgical side * Preoperative upper extremity ultrasound or DSA showed radial artery occlusion and arteriovenous fistula * The diameter of radial artery was still less than 2mm after brachial plexus block * Axillary artery occlusion and other vascular anatomical abnormalities may affect the operation * Radial artery patency: Barbeau type D * The history of hand trauma may affect the establishment of radial artery; access, or the use of radial artery as a bypass or dialysis vessel * patients with incomplete block effect after nerve block were detected; * The patient refused to participate in the study or cooperate with the follow-up

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Assess the RAS by angiography at the begining of the operation

Timeframe: During the operation

Evaluate the degree of RAS by angiography at the end of the operation

Timeframe: During the operation

Trial details

NCT IDNCT06035692

SponsorThe First Affiliated Hospital with Nanjing Medical University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-02-29

Contact for this trial

Feng Feng, M.D

13814073686 316637881@qq.com

View on ClinicalTrials.gov More Intracranial Aneurysm trials