Active — Not RecruitingNot Applicable

Support for Adolescents Living With HIV in South Africa

South Africa570 participantsStarted 2024-02-02

Plain-language summary

This is a cluster randomized controlled trial determining the effectiveness of in-person or mHealth-based adolescent-friendly transition interventions compared to standard care on retention in care and viral suppression among adolescents living with HIV who have low transition readiness. Participants are adolescents living with HIV ages 15 to 19 years old in KwaZulu-Natal, South Africa.

Who can participate

Age range15 Years – 19 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria for Adolescent Participants: * Aged 15 to 19 years at enrollment * Living with perinatally-acquired HIV * Receiving ART for at least 6 months * Aware of their HIV status * Scoring low to intermediate on transition readiness assessment (intervention cohort only) Inclusion Criteria for Healthcare Providers: * Profession as a healthcare provider * Working at one of the designated clinics * Involvement with adolescents before, during or after transition to adult care Exclusion Criteria for all participants: * Inability to read and/or speak English or Zulu * Severe mental or physical illness preventing participation in informed consent activities * Anticipated move out of clinic area in the next 12 months

What they're measuring

Number of Participants Retained in Care

Timeframe: After the 9 month intervention (Month 9 or Month 18)

Change in Number of Participants with Viral Suppression

Timeframe: Baseline, After the 9 month intervention (Month 9 or Month 18)

Trial details

NCT IDNCT06035445

SponsorEmory University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12-31

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