RecruitingNot Applicable

Fetal Cell Receptors Repertoire

France160 participantsStarted 2024-02-06

Plain-language summary

The purpose of this study is to describe the transcriptomic profile of foetal cells in post-partum and more specifically to determine which chemokine receptors are overexpressed in foetal cells in post-partum women with wounds To do so, the investigators will isolate foetal cells from the peripheral blood of healthy controls post partum women as well as from post partum women with skin ulcers and then perform RNA sequencing.

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: Common criteria : * Adult women, * Post-partum: having been pregnant for any length of time, * Having signed a free and informed consent form, * Primiparous or multiparous, * Affiliated to a health insurance Patients : \- Patients with a venous, diabetic or sickle cell ulcer, or mixed ulcer Control group patients : * Volunteers, * Age-matched, * Without skin ulcers. There are no specific criteria for children. Exclusion Criteria: * Minors (for patients) * Under court protection, curatorship, guardianship (for patients) * Immunocompromised patients for any reason whatsoever * Refusal of consent * Refusal of blood and/or saliva samples for themselves or a member of their family

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Transcriptomic analysis by single cell sequencing

Timeframe: Month 1 up to month 5

Trial details

NCT IDNCT06031714

SponsorAssistance Publique - Hôpitaux de Paris

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-07-01

Contact for this trial

Sélim ARACTINGI, MD, PHD

00 33 1 58 41 18 13 selim.aractingi@aphp.fr

View on ClinicalTrials.gov More Venous Ulcer trials

Plain-language summary

Who can participate

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.