2 Weeks of Citrulline Supplementation on Arterial Function in Postmenopausal Women With Elevated Blood Pressure or Hypertension

Inclusion Criteria: * Postmenopausal women (defined as the absence of menstruation for at least 1 year). * Resting systolic blood pressure 120-150 mmHg. * Between the ages of 50 - 70 years. * Sedentary (\< 120 minutes of exercise/week). * Body mass index of 25 - 39.9 kg/m2. * Fasting glucose \< 126 mg/dL and HbA1c \< 6.5%. Exclusion Criteria: * Body mass index ≥ 40 or \< 25 kg/m2. * Systolic blood pressure \> 150 mmHg. * Taking more than two antihypertensive medications. * Cardiovascular diseases, type I/II diabetes, musculoskeletal disorders, or cancer. * Changes in hypertensive medication in the past three months. * Began or changed hormone replacement therapy in the past 6 months. * Current smoker. * Heavy drinking (\> 7 alcoholic drinks/week). * Participants on beta-blockers or other vasodilatory supplements (nitrates). * Incorporated in a weight loss program and/or aerobic or resistance training program.