Stopped: withdrawn
Patients presenting with prosthetic joint infections of a total knee replacement who are treated with an antibiotic spacer will be observed prospectively for their response to treatment and antibiotic elution profiles will be measured post-operatively utilizing mass spectrometry from synovial fluid acquired as part of standard of care in the management of prosthetic joint infection. Secondary outcomes including post-operative complications, re-operation rates, and re-admission rates will also be compared.
Age range
18 Years
Sex
ALL
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Intra-articular Antibiotic Elution Profile
Timeframe: Post-operative day 2 and during 2nd stage re-implantation evaluation (around 10 weeks according to standard of care)