CompletedNot Applicable

Microembolic Detection in Acute Ischemic Stroke Patients With Atrial Fibrillation and Outcome

Portugal61 participantsStarted 2019-06-06

Plain-language summary

This multicenter international prospective cohort study will include patients with AIS with a known or newly diagnosed anticoagulant-naïve AF. All centers will use the same transcranial Doppler machine for one-hour monitoring with bilateral 2-MHz probes within 24 hours of symptom onset. Recordings will be analyzed for MES by a blinded central reader. The primary aim is to determine the proportion of patients with MES and the association of MES with functional outcomes assessed by a modified Rankin scale (mRS) score at 90 days.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * acute ischemic stroke admitted to the Stroke Unit, history of AF/flutter or a new diagnosis of AF at the stroke, and with a possibility to be monitored within 24 hours after symptom onset. Exclusion Criteria: * use of anticoagulants at stroke onset; prosthetic valves; inadequate temporal bone window; uncooperative patients.

What they're measuring

Prevalence of MES

Timeframe: Within 24 hours of symptom onset

Poor functional outcome

Timeframe: 90-days after stroke

Trial details

NCT IDNCT06018090

SponsorCentro Hospitalar De São João, E.P.E.

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2022-08-31

View on ClinicalTrials.gov More Infarction, Brain trials