The Bone-Myoregulation Reflex and Development of Sarcopenia in Osteoporosis (NCT06017245) | Clinical Trial Compass
CompletedNot Applicable
The Bone-Myoregulation Reflex and Development of Sarcopenia in Osteoporosis
Turkey (Türkiye)60 participantsStarted 2023-08-29
Plain-language summary
Bone and skeletal muscle are in a single unit that interacts with each other structurally and functionally. The aim of this study is to determine the contribution of bone myoregulation reflex as a neuronal crosstalk mechanism on the development of sarcopenia in postmenopausal and senile osteoporosis
Who can participate
Age range
20 Years – 85 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* For healthy young adults control Healthy volunteers aged 20-45 years
* For postmenopausal osteoporosis Hip DXA T-score (neck or total hip) \< -2.5
* For the Senile osteoporosis Over 65 years Male Hip DXA T-score (neck or total hip) \< -2.5 Female
Exclusion Criteria:
* Osteopenic cases
* Possible sarcopenia (according to EWGSOP2 criteria)
* Vertigo
* Kidney stone
* Panic attack story
* Secondary osteoporosis
* Those with polyneuropathy, central nervous system disease clinic/history
* Myopathies (steroid, vitamin D deficiency, primary muscle diseases, etc.)
* Cases with lesions on the soleus skin
* History of fracture in lower extremity, joint prosthesis
* Lower extremity active/acute thrombophlebitis
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Bone myoregulation reflex latency
Timeframe: up to 2 weeks
Trial details
NCT IDNCT06017245
SponsorIstanbul Physical Medicine Rehabilitation Training and Research Hospital