RecruitingEarly Phase 1

Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?

United States84 participantsStarted 2023-09-15

Plain-language summary

For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.

Who can participate

Age range18 Years – 85 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Meet ICHD-3 Migraine Headache Criteria * Had a minimum 5-point reduction in headache intensity after nerve block(s) or post- block pain score of 0 to 2 * Nerve block performed with bupivacaine 0.5% Exclusion Criteria: * Head trauma * Suspicion of secondary headache (i.e. stroke, known tumor, glaucoma) * Headache in the setting of viral syndrome * Chronically on steroids * Known allergy to dexamethasone * Unable to reach the patient by phone or text for follow-up * Gestational diabetes or other uncontrolled diabetes * Known to be immunocompromised

What they're measuring

Recurrence of headache

Timeframe: 72-96 hours post treatment

Trial details

NCT IDNCT06016465

SponsorTexas Tech University Health Sciences Center, El Paso

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-12-30

Contact for this trial

Edward Michelson, MD

915 215 4600 edward.michelson@ttuhsc.edu

View on ClinicalTrials.gov More Migraine trials