CompletedPhase 1/2

Effect of Local Application of Simvastatin Versus Bone Powder on Implant Bone Changes

Egypt24 participantsStarted 2021-01-05

Plain-language summary

This study is conducted A- To investigate that PRF loaded with osteopromotive pharmacological drug can be a great aid in implant rehabilitation, and whether it could be a replacement for the other high price bone graft materials or not. This will be done through: 1. Measuring bone changes around the implant by cone beam 2. Measuring change in bone density around the implants B- Evaluate the effect of statins on osteoblasts activity and expression of various osteogenic products in vitro.

Who can participate

Age range45 Years – 60 Years

SexMALE

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Badly Broken Down Tooth requiring extraction * Medically Free * Any other procedures or surgeries were performed 6 months earlier Exclusion Criteria: * patients with systemic diseases affecting bone quality or resorption * temporomandibular joint dysfunction * severe attrition or parafunctional habits * patients undergoing radiotherapy or chemotherapy * heavy smokers * vulnerable groups like psychologically unstable patients.

What they're measuring

Changes in crestal peri-imlant Bone

Timeframe: 12 months

Trial details

NCT IDNCT06016218

SponsorBritish University In Egypt

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2022-01-05

View on ClinicalTrials.gov More Dental Caries Extending to Pulp trials