CompletedNot Applicable

Effect of Sourdough Bread Consumption on Postprandial Responses, Appetite Regulation and Energy Intake

Belgium47 participantsStarted 2024-01-01

Plain-language summary

During this project the effect of yeast bread and sourdough breads consumption on satiety, energy intake at subsequent meal and postprandial metabolic responses, will be investigated.

Who can participate

Age range

18 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Female and male participants * age range 18 - 50 * BMI range 18.5 - 25.0 kg/m2 at screening visit * Regular eating pattern (3 meals per day on at least 5 days per week) * Stable body weight for the last 6 months Exclusion Criteria: * Currently smoking (has smoked in the last 28 days) or willingness to smoke during the study period * Pregnancy, lactation or wish to become pregnant during the study period * Family history of diabetes * Previous or current gastrointestinal or endocrine disorders * Previous or current substance/alcohol dependence or abuse (\> 2 units per day/14 units per week) * Coeliac disease or gluten sensitivity * Use of pre- or probiotics within one month preceding the study * Use of antibiotics within 3 months preceding the study * Excessive concern about eating habits or body weight as evidenced from scores \< 18 on the restraint and disinhibition subscales of the Three-Factor Eating Questionnaire (Stunkard \& Messick, 1985)

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Appetite measurements

Timeframe: During test day 1 (up to 4 hours)

Appetite measurements

Timeframe: During test day 2 (up to 4 hours)

Food intake at subsequent meal

Timeframe: During test day 1 (240 minutes after ingestion of breakfast)

Food intake at subsequent meal

Timeframe: During test day 2 (240 minutes after ingestion of breakfast)

Trial details

NCT IDNCT06015867

SponsorKU Leuven

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-04-28

View on ClinicalTrials.gov More Appetite trials

Who can participate

Age range

18 Years – 50 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

What they're measuring

Appetite measurements

Timeframe: During test day 1 (up to 4 hours)

Appetite measurements

Timeframe: During test day 2 (up to 4 hours)

Food intake at subsequent meal

Timeframe: During test day 1 (240 minutes after ingestion of breakfast)

Food intake at subsequent meal

Timeframe: During test day 2 (240 minutes after ingestion of breakfast)