This study aimed to understand whether metformin therapy can improve insulin resistance in adolescent PCOS patients, both during treatment and after discontinuation, and to evaluate its action on the hormonal and metabolic pathways.
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Insulin resistance change in eighty hyperinsulinemic patients after metformin therapy and its discontinuation
Timeframe: about 3 years
Androgen levels change in eighty hyperinsulinemic patients after metformin therapy and its discontinuation
Timeframe: about 3 years