Ciprofol vs Propofol for Reducing Hypoxia Incidence in ERCP (NCT06015074) | Clinical Trial Compass
UnknownNot Applicable
Ciprofol vs Propofol for Reducing Hypoxia Incidence in ERCP
China136 participantsStarted 2024-06-15
Plain-language summary
Intravenous anesthesia has been widely used in endoscopic retrograde cholangiopancreatography (ERCP). In the past decade, many practices have been carried out under the propofol-based monitored anesthesia care without endotracheal intubation in patients undergoing ERCP.
Ciprofol is a newly developed intravenous anesthetic with a potency 4-5 times than that of propofol. Ciprofol seems a promising anesthetic agent for intravenous anesthesia but the evidence supported its application in ERCP is still limited.
Who can participate
Age range
18 Years – 80 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* patients undergoing ERCP, ASA I-III
* normal renal function
* BMI ≥ 18kg/m 2 and ≤ 30kg/m 2
Exclusion Criteria:
* Previous serious cerebrovascular accidents and other neurological diseases
* mental diseases, long-term use of drugs that affect the function of the central nervous system, benzodiazepines or opioids
* history of anesthetic allergy
* preoperative hypotension or preoperative SpO2 \< 90%, or chronic respiratory failure
* patients suspected of having difficult airways
* screening for drug addiction and alcohol abuse within the first 3 months (\> = 6standarddrinks/day)
* patients diagnosed with severe cardiopulmonary disease, or respiratory or respiratory diseases such as sleep apnea syndrome;
* bradycardia or atrioventricular block.
* participate in other clinical trials within 4 weeks;
* cognitive or communication abnormalities determined by the researchers;
* emergent and critical conditions during the operation;
* other conditions that the researchers believe are not suitable to participate in the study.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
the incidence of hypoxia
Timeframe: from the induction of anesthesia to the patient leaving the postanesthesia care unit，about an average of 1.5 hours