Low-intensity Versus Medium-intensity Continuous Kidney Replacement Therapy for Critically Ill Patients

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1. 1This trial is comparing two different intensities of continuous kidney replacement therapy — low versus medium — so what does that actually mean for how much time I'd spend connected to the machine each day, and how would that fit with my current condition in the ICU?
2. 2The main thing this trial is measuring is a combination of death and how long I'd need kidney replacement therapy over 28 days — given where I am right now, what does my doctor think my realistic outlook looks like on either of those two measures?
3. 3Since this is a Phase 2/3 trial, there's still some uncertainty about whether one intensity is clearly safer or more effective than the other — are there already any preliminary findings or safety signals my doctor is aware of that might point toward one approach being better for someone in my situation?
4. 4Would I be randomly assigned to low- or medium-intensity treatment without my care team being able to choose based on my specific needs, and is there any risk that the assigned intensity might not be the best match for how severe my kidney injury is?
5. 5Before considering this trial, should I ask whether the standard of care my hospital already uses — either low or medium intensity — might be just as good an option for me, without the uncertainties that come with being part of a research study?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.