The goal of this clinical trial is to evaluate the effectiveness of ketogenic diet in patients with MELAS syndrome. The main questions it aims to answer are: Clarify the curative effects of ketogenic diet in the treatment of MELAS disease. Prevent the aggravation of MELAS disease, and improve the quality of life of patients. Provide reliable evidence-based medical basis for the clinical application of ketogenic diet in the treatment of MELAS syndrome patients. The clinical data of the participants treated with ketogenic diet will be collected, including the completion of ketogenic diet and clinical data at the start of treatment and after 1 month, 3 months, 6 months and 12 months
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Change from Baseline Clinical Symptom Score in 1 Year
Timeframe: Baseline, 1 month, 3 months, 6 months and 12 months
Change from Baseline Biochemical indicators in 1 Year
Timeframe: Baseline, 1 month, 3 months, 6 months and 12 months
Change from Baseline Biochemical indicators in 1 Year
Timeframe: Baseline, 1 month, 3 months, 6 months and 12 months
Hamilton Anxiety Scale (HAMA)
Timeframe: Baseline, 1 month, 3 months, 6 months and 12 months
Hamilton Depression Scale(HAMD
Timeframe: Baseline, 1 month, 3 months, 6 months and 12 months
Wechsler Intelligence Scale(WISC)
Timeframe: Baseline, 1 month, 3 months, 6 months and 12 months
Mini-mental State Examination(MMSE)
Timeframe: Baseline, 1 month, 3 months, 6 months and 12 months
Change from Baseline Diagnostic Examination in 1 Year
Timeframe: Baseline, 1 month, 3 months, 6 months and 12 months