Maternal Brain Imaging in Opioid Use Disorder

Pregnant Women with OUD Inclusion Criteria: * Age: \>18 years old * Any subject that is currently on Buprenorphine at time of screening * Singleton pregnancy Exclusion Criteria: * Serious maternal medical illness * HIV or AIDs * Polysubstance use * Score \>9 on the PHQ-9, and score \>0 on item 9 which is about suicidality * Score of 8 or more on GAD-7 * Any contraindications for MRI * Known or suspected major fetal congenital abnormalities Pregnant Women with no history of OUD Inclusion: * Age: \>18 years old * Singleton pregnancy Exclusion: * Serious maternal medical illness * HIV or AIDS * Score of \>9 on the PHQ-9, and a score of \>0 on item 9 which is about suicidality * Score of 8 or more on GAD-7 * Known or suspected major fetal congenital abnormalities * Any contraindications for MRI * Opioid or polysubstance abuse as identified on urine screening