RecruitingPhase 4

Hydroxycitrate: A Novel Therapy for Calcium Phosphate Urinary Stones

United States25 participantsStarted 2023-12-13

Plain-language summary

This study tests whether hydroxycitrate, a molecule closely related to citrate, can reduce calcium phosphate stone recurrence.

Who can participate

Age range21 Years – 99 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: \- Calcium Phosphate stone formers Exclusion Criteria: * History of recurrent urinary tract infections * Chronic diarrhea * Estimated Glomerular Filtration Rate (eGFR) \< 45 ml/min/1.73 m2 * History of primary hyperparathyroidism * Hypokalemia * Hyperkalemia * Pregnancy

What they're measuring

Formation product (FP) for Calcium Phosphate

Timeframe: After 1 week of treatment

Trial details

NCT IDNCT06003348

SponsorUniversity of Texas Southwestern Medical Center

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-05-31

Contact for this trial

NAIM M MAALOUF, MD

214/648-2954 naim.maalouf@utsouthwestern.edu

View on ClinicalTrials.gov More Calcium Phosphate Kidney Stones trials