CompletedNot Applicable

Eggs for Gut Health

Sierra Leone461 participantsStarted 2023-10-09

Plain-language summary

The goal of this clinical trial is to test egg powder supplementation in children with moderate acute malnutrition in Sierra Leone. The main question it aims to answer is: \- Will provision of 15g of whole egg powder per day during and after treatment for moderate acute malnutrition (for 24 weeks total) improve small intestinal permeability and linear growth among 6-30 month old Sierra Leonean children compared with daily corn powder supplementation?

Who can participate

Age range6 Months – 30 Months

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * At least 6 months of age and less than 30 months of age * Mid-upper arm circumference \>= 11.5cm and \< 12. 5 cm * Mid-upper arm circumference-for-age z-score \< -2 * Provision of signed (or thumb-printed) and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study, including no plan to move from the catchment area of a participating clinic Exclusion Criteria: * Nutritional edema * Simultaneous involvement in another research trial or supplementary feeding program * Chronic debilitating illness * Allergy to egg * Receipt of treatment for acute malnutrition within 1 month prior to screening

What they're measuring

Percent lactulose excretion

Timeframe: Collected 12 and 24 weeks after enrollment

Change in length-for-age z-score

Timeframe: To be compared at 12 and 24 weeks after enrollment

Trial details

NCT IDNCT06002438

SponsorWashington University School of Medicine

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-12-19

View on ClinicalTrials.gov More Moderate Acute Malnutrition trials