CompletedPhase 2

Superficial Cervical Plexus Block and Quality of Recovery After Thyroidectomy

United States160 participantsStarted 2023-11-27

Plain-language summary

The goal of this clinical trial is to learn whether a superficial cervical plexus block improves quality of recovery after thyroid surgery. Investigators will compare a superficial cervical plexus block with bupivacaine compared to an identical procedure performed saline placebo to see if there is a difference in quality of recovery on the first postoperative day. The main question to answer is: • Does a superficial cervical plexus block with bupivacaine compared to placebo improve quality of recovery in patients having thyroid surgery. Participants will: * Fill out an initial preoperative survey * Be randomized to receive a superficial cervical plexus block with bupivacaine or saline placebo while under anesthesia before the surgery starts * Fill out a survey about recovery on the first day after surgery

Who can participate

Age range

18 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Aged 18 years or older * American Society of Anesthesiologists Physical Status classification I-III * Provision of signed and dated informed consent form * Stated willingness to comply with all study procedures and availability for the duration of the study * Scheduled for thyroid surgery * Access to smartphone device or computer with internet connection and has an email address Exclusion Criteria: * Non-English speaking * American Society of Anesthesiologists Physical Status classification \> III * Have an intolerance or contraindication to the medications involved in the study * Undergoing repeat thyroid surgery * Undergoing surgery with planned neck dissection * Plan for admission post-operatively * Positive pregnancy test on day of surgery (for participants with child-bearing potential) * Refusal to participate

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Quality of Recovery-40 (QoR-40) questionnaire score on postoperative day (POD) 1

Timeframe: Up to 2 days

Trial details

NCT IDNCT06002152

SponsorYale University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2026-02-03

View on ClinicalTrials.gov More Postoperative Pain trials