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Detecting the Rest Tremor Associated With Parkinson's Disease Using Analysis of the Muscle Contractions Rhythmicity

France80 participantsStarted 2023-04-03

Plain-language summary

Resting tremors associated with Parkinson's disease (PD) remains difficult to quantify and track during disease progression. This study propose to explore the rhythmicity of distal muscle contractions in the upper limb to characterize resting tremor and discriminate it from cerebellar tremor (CT) based on the frequency spectrum of the EMG signal.

Who can participate

Age range18 Years – 100 Years

SexALL

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AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patient who performed surface EMG recordings of wrist flexor-pronators and extensor-supinators in Laboratories; * diagnosis of Parkinson's disease or cerebellar tremor. Exclusion Criteria: * Botulinium toxin injection in upper limb during a delay of 3 months before surface EMG recordings; * Levodopa drugs administrated during a delay of 12 hours before surface EMG recordings; * Tremor-favour drugs administrated during a delay of 30 days before surface EMG recordings; * Presence of an other neurologic disease or of any disease associated with motor disorders in upper limb.

What they're measuring

rhythmicity index

Timeframe: 10 seconds

Trial details

NCT IDNCT05998486

SponsorHenri Mondor University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-09-30

Contact for this trial

Emilie Hutin, PhD

+33149812549 emilie.hutin@aphp.fr

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