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Detecting the Rest Tremor Associated With Parkinson's Disease Using Analysis of the Muscle Contractions Rhythmicity

France80 participantsStarted 2023-04-03

Plain-language summary

Resting tremors associated with Parkinson's disease (PD) remains difficult to quantify and track during disease progression. This study propose to explore the rhythmicity of distal muscle contractions in the upper limb to characterize resting tremor and discriminate it from cerebellar tremor (CT) based on the frequency spectrum of the EMG signal.

Who can participate

Age range

18 Years – 100 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * patient who performed surface EMG recordings of wrist flexor-pronators and extensor-supinators in Laboratories; * diagnosis of Parkinson's disease or cerebellar tremor. Exclusion Criteria: * Botulinium toxin injection in upper limb during a delay of 3 months before surface EMG recordings; * Levodopa drugs administrated during a delay of 12 hours before surface EMG recordings; * Tremor-favour drugs administrated during a delay of 30 days before surface EMG recordings; * Presence of an other neurologic disease or of any disease associated with motor disorders in upper limb.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

rhythmicity index

Timeframe: 10 seconds

Trial details

NCT IDNCT05998486

SponsorHenri Mondor University Hospital

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2023-09-30

Contact for this trial

Emilie Hutin, PhD

+33149812549 emilie.hutin@aphp.fr

View on ClinicalTrials.gov More Parkinson trials