RecruitingNot Applicable

LiverPAL: A Trial of Inpatient Palliative Care for Patients With Advanced Liver Disease

United States200 participantsStarted 2023-09-20

Plain-language summary

The goal of this clinical trial is to evaluate whether early integration of palliative care in the care of hospitalized patients with advanced liver disease (AdvLD) can improve patients' quality of life, physical symptoms, mood, and serious illness communication. Palliative care is a medical specialty focused on lessening (or "palliating") symptoms and assisting in coping with serious illness.

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. Hospitalized patient with a diagnosis of advanced liver disease, defined as cirrhosis with one of the following (new or ongoing) within the prior six months from date of consent:
✓. Ability to comprehend English

Exclusion criteria

✕. Prior history of liver transplantation
✕. Have uncontrolled hepatic encephalopathy, cognitive impairment, psychiatric disorder or other comorbid condition which the primary medical, hepatology, and/or transplant surgery teams believes prohibits the ability to provide informed consent
✕. Current or recent (within 5 years of receiving curative cancer treatment) history of extrahepatic malignancy (excluding non-melanoma skin cancer)
✕. Presence of hepatocellular carcinoma beyond Milan criteria
✕. Are already receiving hospice care
✕. Receive a score of \<10 on the Simplified Animal Naming Test
✕. Adult caregiver (≥ 18 years of age)
✕. A relative or friend identified by the patient upon whom the patient relies for help and who likely is to be present in-person during hospitalizations or clinic appointments, or willing to participate by phone

What they're measuring

Patient Quality of Life (Functional Assessment of Chronic Illness Therapy - Palliative Care, FACIT-Pal) up t0 4 weeks

Timeframe: Up to 4 weeks

Trial details

NCT IDNCT05998330

SponsorMassachusetts General Hospital

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2027-07

Contact for this trial

Grace Bizup, BA

617-724-1316 gbizup@mgh.harvard.edu

View on ClinicalTrials.gov More Liver Disease Chronic trials