Efficacy and Safety of Etoricoxib-tramadol Tablet in Acute Postoperative Pain

Inclusion Criteria: * Patients of both sexes aged from 18 to 40 years. * Patients who agreed to participate in the study by signing the informed consent. * Patients with indication for surgical extraction of impacted lower third molars according to the Pell and Gregory classification. * Healthy subjects or with history of controlled chronic non-communicable diseases or that can be controlled prior to surgery, which, in the investigator's opinion, do not represent an additional risk for the patient. * Patients who, at the investigator's discretion, meet personal and family conditions that allow them to properly comply with the activities described in the protocol and adherence to treatment. Exclusion Criteria: * Findings in the clinical history, vital signs, physical examination or laboratory studies suggesting abnormal conditions which represent a risk for subject's health at the investigator´s discretion. * Hypersensitivity to any of the active ingredients and/or excipients of the investigational drugs. * Patients with active peptic or gastroduodenal ulcer or diagnosis 30 days prior to signing the informed consent. * Patients with history of allergic asthma reactions. * Patients with severe hepatic dysfunction, classified as Child Pugh C or when being less, the investigator considers it an additional risk for patients. * Patients with a creatinine clearance \<30 mL/min. * Patients with coagulation disorders. * Patients with Systemic Lupus Erythematosus. * Patients with co…