The Effects of Troponin I Surveillance Among Patients Undergoing Acute High-risk Abdominal Surgery (NCT05992961) | Clinical Trial Compass
CompletedNot Applicable
The Effects of Troponin I Surveillance Among Patients Undergoing Acute High-risk Abdominal Surgery
Denmark558 participantsStarted 2018-02-01
Plain-language summary
Treatment of disorders such as gastrointestinal tract (GI) perforation, ischemia and obstruction often require acute high-risk abdominal surgery, which is associated with a high risk of complications such as myocardial injury after non-cardiac surgery (MINS) and mortality. The majority of patients with MINS will not experience any symptoms, and thus MINS remains undetected without routine troponin measurements.
The investigators hypothesized that implementing surveillance with troponin I as a standard care might be useful as risk stratification, and that increased surveillance, examinations, and subsequent individually based medical interventions, might improve the outcomes for patients with MINS.
Who can participate
Age range
18 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* Eligible patients were 18 years or older
* Undergoing surgery for gastrointestinal perforation, obstruction, mesenterial ischemia or necrosis, or anastomotic leakage.
Exclusion Criteria:
* Not undergoing surgery for one of the conditions above
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1This trial has already completed — does that mean there are published results showing whether routine troponin I monitoring after emergency abdominal surgery actually reduced deaths, and could those results change how my care team would monitor me?
2Since this study looked specifically at patients undergoing high-risk emergency abdominal surgery, how does my specific situation compare to the types of patients enrolled, and would troponin I surveillance even be considered part of my standard care plan?
3The trial was focused on detecting myocardial injury after non-cardiac surgery — what does it actually mean if my troponin levels come back elevated after an abdominal operation, and what follow-up steps would my care team take?
4Because this was a Phase NA observational-style study comparing outcomes before and after a monitoring protocol was introduced, does it tell us anything definitive about whether troponin surveillance causes better outcomes, or just that it's associated with them — and how should I weigh that when thinking about my own treatment?
5Are there standard-of-care guidelines already in place for troponin monitoring after emergency abdominal surgery, and would my hospital routinely follow those regardless of this trial's findings?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
compare the mortality rate before and after implementing troponin I surveillance