Air-polishing With Erythritol During Orthodontic Tretament

Inclusion Criteria: * Subjects about to undergo fixed orthodontic treatment will be invited to participate. * Age between 12 and 16 years only participants * Informed written consent obtained by the parents Exclusion Criteria: * Clinically significant concomitant disease states (e.g., renal failure, hepatic dysfunction, cardiovascular disease, etc.), * Known or suspected non-compliance, drug or alcohol abuse * Inability to follow the procedures of the investigation, e.g. due to language problems, psychological disorders, dementia, etc. of the subject * Participation in another investigation with an investigational drug or another MD within the 30 days preceding and during the present investigation * Previous enrolment into the current investigation * Enrolment of the PI, his/her family members, employees and other dependent persons * History of fixed orthodontic treatment * Defects on enamel on labial surfaces of the teeth * Untreated cavitated lesions * Plaque levels \>25% * Periodontitis * Multiple missing teeth * Cleft lip and/or palate or other craniofacial anomalies or syndromes * Patients taking any regular medication * Patients with asthmatic problems