CompletedNot Applicable

Effect of Epigallocatechin-3-Gallate Solution as a Root Canal Irrigant on Post-Operative Pain Intensity and Bacterial Load Reduction in Necrotic Tooth

Egypt40 participantsStarted 2023-10-01

Plain-language summary

clinically compare the intensity of post-operative pain and the amount of bacterial load reduction after using 20% Epigallocatechin-3-gallate solution during chemomechanical preparation, versus 2.5% NaOCl, in asymptomatic necrotic mandibular premolars treated in a single visit.

Who can participate

Age range18 Years – 45 Years

SexALL

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Inclusion criteria

✓. Systematically healthy patient (ASA I, II).
✓. Age between 18 and 45 years
✓. Male or female.
✓. Asymptomatic mandibular premolar teeth diagnosed with pulp necrosis.

Exclusion criteria

✕. Medically compromised patients having significant systemic disorders. (ASA III or IV).
✕. Teeth with:
✕. Patients who could not interpret the NRS.

What they're measuring

Postoperative pain

Timeframe: Postoperative pain measured at 6, 12, 24, 48 hours after single visit treatment.

Trial details

NCT IDNCT05988788

SponsorCairo University

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-07-30

View on ClinicalTrials.gov More Necrotic Pulp trials