The Role of Fatty Acids in Vaccine Efficacy (NCT05987384) | Clinical Trial Compass
CompletedNot Applicable
The Role of Fatty Acids in Vaccine Efficacy
China45 participantsStarted 2023-05-03
Plain-language summary
This study intends to use a randomized controlled trial design to vaccinate all participants against rabies and perform ARA interventions during vaccination to test the efficacy, safety, and intestinal flora of each group after immunization.
Who can participate
Age range
18 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
* 1）18-45 years old;
* 2）BMI 18.5-24.9 kg/m2;
* 3）Have not received rabies vaccination.
Exclusion Criteria:
* 1\) Those who have severe disorders of abnormal lipid metabolism;
* 2\) Those who have used lipid-lowering drugs, weight loss drugs, and insulin drugs in the past three months;
* 3\) Those who have received other vaccines in the past three months;
* 4\) Those who have used probiotics or prebiotics in the past three months;
* 5\) Those who have used steroids and immunosuppressants, other hormonal drugs in the past year;
* 6\) Those with immunodeficiency diseases;
* 7\) Those with a history of severe vaccine allergies;
* 8\) Those who have disorders of liver and kidney metabolism;
* 9\) Those who have had fever, cold, severe diarrhea and other diseases in the past month.
* 10\) Smokers in the last year.
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.