A Study of the Feasibility of Using the Dietary Supplement "ARTNEO" in Patients With Osteoathritis

Inclusion criteria

• ✓. Voluntarily signed informed consent to participate in the study;
• ✓. Men and women in postmenopause, aged 40-75 years, capable of independent movement, BMI 18-30 kg/m2;
• ✓. Verified primary gonarthrosis according to the American College of Rheumatology criteria at least 6 months before enrollment in the study (in the presence of pain in the knee joint and radiological signs of gonarthrosis in combination with one of the following signs: crepitus in the joint or morning stiffness in the joint for less than 30 min);
• ✓. II-III radiological stage of gonarthrosis according to the Kellgren-Lawrence classification with a predominant lesion of the medial tibiofemoral area of the knee joint;
• ✓. Severity of pain in the assessed knee joint at the time of the screening visit from 40 or more on 100-mm VAS while walking;
• ✓. Ability to understand the rules of the study, willingness to follow them;
• ✓. Willingness to limit the diet (soy, avocado, passion fruit, pineapple, turmeric, linseed, rapeseed, soybean oils, chia seeds, walnuts, decoction of willow bark, pine, wormwood, L-carnitine, etc. should be excluded);
• ✓. Consent of the men during the study and within 30 days after its completion to use the methods of contraception described in the protocol of this study.