UnknownNot Applicable

Role of Topical Vancomycin in Reducing Infections in Hip and Knee Arthroplasty

Poland1,000 participantsStarted 2022-07-01

Plain-language summary

The study is designed to assess the efficacy of vancomycin powder and dilute povidone-iodine lavage (VIP protocol) in reducing the PJI after primary Total Hip Arthroplasty (THA) and Total Knee Arthroplasty (TKA). We hypothesized that VIP protocol provides superior reduction of periprosthetic joint infection (PJI) rates after primary THA and TKA compared with diluted povidone-iodine (PI) protocol.

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * undergoing THA or TKA as a result of osteoarthritis or rheumatoid arthritis, can understand and comply with the study protocol, have signed the informed consent document at screening Exclusion Criteria: * Patients referred to the hospital in order to undergo THA or TKA due to different reason than osteoarthritis, rheumatoid arthritis or avascular necrosis of the femoral head, such as: failed femoral neck fractures, displaced acetabular fractures or revision acetabular fractures, revision knee or hip arthroplasty

What they're measuring

periprosthetic joint infection

Timeframe: 90 days

Trial details

NCT IDNCT05972603

SponsorIndependent Public Healthcare Center in Rypin

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-06

View on ClinicalTrials.gov More Osteoarthritis, Knee trials