CompletedNot Applicable

Endoscopic Surveillance on a High-risk Population for Gastric Cancer in Latin America: The ECHOS Cohort Study.

Chile685 participantsStarted 2015-06-01

Plain-language summary

The goal of this observational study is to evaluate the risk factors associated with incident HGD/GA in patients with CAG with or without IM who are enrolled in endoscopic surveillance, as well as to compare GA incidence according to the OLGA and OLGIM scales in patients 18 years or older. . The main questions it aims to answer are: * What risk factors are associated with incident HGD/GA in patients with CAG with or without IM? * What is the comparative HGD/GA incidence according to the OLGA and OLGIM scales?

Who can participate

Age range18 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * At least one non-urgent outpatient esophagogastroduodenoscopy (EGD) with gastric biopsies collected following the Updated Sydney System Biopsy Protocol (USSBP) between June 2015 and June 2021. * Underwent a subsequent "surveillance" EGD. For the subsequent EGD to qualify as surveillance, it needed to occur at least six months after the baseline EGD and include gastric biopsies collected according to the USSBP; one exception to the USSBP requirement was if HGD or GA was detected on the surveillance. Exclusion Criteria: * Prior history of HGD or any type of gastric malignancy, gastrectomy, or non-gastric active malignancy. * HGD or GA on the baseline EGD was excluded.

What they're measuring

High grade dysplasia/Gastric adenocarcinoma

Timeframe: At least 6 months between first and second EGD, assessed up to 96 months

Trial details

NCT IDNCT05969444

SponsorPontificia Universidad Catolica de Chile

Sponsor typeOTHER

Study typeOBSERVATIONAL

Primary completion2021-06-30

View on ClinicalTrials.gov More Gastric Cancer trials