RecruitingNot Applicable

Physiologic Cardiac Pacing to Prevent Left Ventricular Dysfunction Post TAVI

Poland500 participantsStarted 2024-02-27

Plain-language summary

The study aims to compare permanent Conduction System Pacing (CSP) with the standard therapy - Right Ventricular Pacing (RVP) or Biventricular Pacing (BVP) - in preventing the development and progression of symptomatic Chronic Heart Failure (CHF) and improving survival in patients after Transcatheter Aortic Valve Implantation (TAVI).

Who can participate

Age range18 Years

SexALL

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Inclusion criteria

✓. transcatheter aortic valve implantation (TAVI) in up to 30 days before qualification to pacemaker implantation
✓. Fulfilled criteria for permanent pacemaker implantation according do 2021 ESC guidelines
✓. Written informed consent
✓. Age of at least 18 years

Exclusion criteria

✕. Permanent pacemaker implantation before TAVI procedure
✕. The occurrence of conduction disturbances more than 30 days after TAVI procedure
✕. No written informed consent
✕. Inability to obtain informed consent from participant
✕. Predicted inability to obtain cooperation from patient during observation period

What they're measuring

Heart Failure Hospitalization

Timeframe: 12 months

All-cause death

Timeframe: 12 months

Trial details

NCT IDNCT05966675

SponsorMedical University of Silesia

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2028-05

Contact for this trial

Krzysztof S. Gołba, MD PhD

+48 (32)359-88-93 krzysztof.golba@gmail.com

View on ClinicalTrials.gov More Atrioventricular Block, Second and Third Degree trials