The Effects on Physical Activity on Mitochondrial Function in Skin Fibroblasts in Patients with Parkinson's Disease.

Inclusion Criteria: * Patients with a medical diagnosis of idiopathic PD, Hoehn and Yahr scale stages of I-III. * Patients who score ≥26 on the Montreal Cognitive Assessment (MoCA). * Patients who have signed the IC. * Patients with stable medication. * Age between 50 and 70 years, and able to walk independently for 6 minutes. Exclusion Criteria: * Patients with a pathology other than idiopathic PD. * Patients with cognitive impairment (MoCA \<26 points). * Patients with uncontrolled cardiovascular disease, visual impairment, or recent musculoskeletal disorders in the extremities. * Patients who are performing another therapeutic exercise protocol. * Patients who have undergone surgery to influence any symptom from the PD.