Active — Not RecruitingNot Applicable

The Effects on Physical Activity on Mitochondrial Function in Skin Fibroblasts in Patients with Parkinson's Disease.

Spain24 participantsStarted 2023-09-01

Plain-language summary

The aim of this study is to investigate the effect of physical activity on mitochondrial function in skin fibroblasts in patients with Parkinson's disease.

Who can participate

Age range

50 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Patients with a medical diagnosis of idiopathic PD, Hoehn and Yahr scale stages of I-III. * Patients who score ≥26 on the Montreal Cognitive Assessment (MoCA). * Patients who have signed the IC. * Patients with stable medication. * Age between 50 and 70 years, and able to walk independently for 6 minutes. Exclusion Criteria: * Patients with a pathology other than idiopathic PD. * Patients with cognitive impairment (MoCA \<26 points). * Patients with uncontrolled cardiovascular disease, visual impairment, or recent musculoskeletal disorders in the extremities. * Patients who are performing another therapeutic exercise protocol. * Patients who have undergone surgery to influence any symptom from the PD.

Questions worth asking your doctor

Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.

1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?

Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.

Questions for the trial coordinator

The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.

1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?

A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.

What they're measuring

Change in oxygen consumption rate

Timeframe: Beginning of the study and after 4 months

Change in ATPmax levels

Timeframe: Beginning of the study and after 4 months

Trial details

NCT IDNCT05963425

SponsorUniversity Ramon Llull

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-05-31

View on ClinicalTrials.gov More Parkinson's Disease trials

Who can participate

Age range

50 Years – 70 Years

Sex

ALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.