Subclinical Impairment of Cardiovascular System in Patients With Psoriasis (NCT05957120) | Clinical Trial Compass
CompletedNot Applicable
Subclinical Impairment of Cardiovascular System in Patients With Psoriasis
Slovenia100 participantsStarted 2022-01-03
Plain-language summary
A cross-sectional study will be conducted, which will include 80 young patients with psoriasis, aged 30-45 years, treated with five different types of antipsoriatic treatment, and 20 healthy patients. All 100 subjects will be subjected to anthropometric measurements, blood will be collected for laboratory tests, and an imaging test will be performed to determine the function of the endothelium and arterial stiffness. The results will then be statistically analyzed.
Who can participate
Age range
30 Years – 45 Years
Sex
ALL
See this in plain English?
AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.
Inclusion Criteria:
\- patients with psoriasis aged 30 to 45 years in stable phase of the disease for at least last 6 months
Exclusion Criteria:
* any treatment besides treatment of psoriasis
* carotid disease
* heart failure
* atrial fibrillation
* diabetes type 1 or 2
* cardiovascular event in the past
* chronic kidney disease stage 3, 4, 5 or end-stage kidney disease
* psoriatic arthritis or any other rheumatic disease
* malignancy
* menopause in women
* other chronic inflammatory diseases
Questions worth asking your doctor
Bring these to your next appointment. They're a starting point for a shared conversation — not a sign you qualify or a recommendation to enrol.
1Based on my diagnosis and history, is this trial worth exploring for me — or is there a standard treatment we should try first?
2What does this trial's phase tell us about how much is already known about its safety and benefit?
3What would taking part actually involve for me — visits, tests, time, and travel?
4What are the known and possible risks or side effects I should weigh, and how would they be monitored?
5If this trial isn't the right fit, what other options or trials would you suggest I look into?
Generated to help you prepare — always confirm anything about your own eligibility and care with the study team and your doctor.
Questions for the trial coordinator
The trial coordinator is the person who runs the study day to day. These cover the practical side — logistics, costs, and what taking part would actually mean for your life. The study team confirms whether you meet the criteria; these are questions to ask, not a sign you qualify.
1What does taking part actually involve week to week — how many visits, where, and how long does each one take?
2What costs are covered by the study, and what might I have to pay for myself, including travel, parking, or time off work?
3What happens during screening, and what happens if the study team confirms I don't meet the criteria after those tests?
4Who pays for the scans, blood work, and other tests the trial requires — the study, my insurance, or me?
5How will being in the trial affect my regular care, and will my own doctor stay informed and involved?
6Can I leave the trial at any point if I change my mind, and what would happen to my care if I do?
A starting point for the conversation — always confirm anything about your own eligibility, costs, and care with the study team and your doctor.
What they're measuring
1
Arterial function - endothelial function
Timeframe: through study completion, an average of 6 months
2
Arterial function - arterial stiffness
Timeframe: through study completion, an average of 6 months
3
Endothelial activation
Timeframe: through study completion, an average of 6 months