CompletedNot Applicable

A Study of Spoken Language in Mania

United States17 participantsStarted 2023-04-27

Plain-language summary

This research is being done to find if there are changes with voice and speech during episodes of mania.

Who can participate

Age range18 Years – 65 Years

SexALL

See this in plain English?

AI-rewrites the medical criteria so a patient or caregiver can understand them. Always confirm with the trial site.

Inclusion Criteria: * Provision of informed consent before any study procedures are performed * English speaker * Documented clinical diagnosis for Bipolar I Disorder * Undergoing hospitalization, or boarding in the Emergency Department, for mania as determined by primary clinical staff Exclusion Criteria: * Positive urine drug screen for amphetamines or cocaine. * Expressing paranoid delusions regarding electronic surveillance. * Documented clinical diagnosis of developmental delay. * Currently involuntarily hospitalized. * Deemed at risk for aggression. * Failure to comprehend study objectives via comprehension questionnaire. * Individuals who have a guardian and are unable to consent for themselves. * Current communicable disease requiring isolation.

What they're measuring

Acoustic Differences

Timeframe: Approximately 48 hours after taking antimanic medications until up to end of subject participation approximately 1 month from enrollment

Syntactical Differences

Timeframe: Approximately 48 hours after taking antimanic medications until up to end of subject participation approximately 1 month from enrollment

Semantic Differences

Timeframe: Approximately 48 hours after taking antimanic medications until up to end of subject participation approximately 1 month from enrollment

Trial details

NCT IDNCT05956340

SponsorMayo Clinic

Sponsor typeOTHER

Study typeINTERVENTIONAL

Primary completion2024-09-06

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